r/Semaglutide: rules, karma requirements and posting culture

Who posts here

Many posts come from people on their first few weeks asking what to expect, and those get patient, friendly answers instead of a link to the search bar. Regulars talk easily about titration, stalls, food noise and switching between GLP-1 drugs, so there is a working vocabulary, but nobody is turned away for not knowing it. A basic question stays up and gets answered; it just may get fewer replies than a progress photo.

• Patients just starting a prescription who want to know what the first weeks feel like.
• Longer-term users posting progress photos, stalls and maintenance questions.
• People with type 2 diabetes or PCOS for whom weight is one part of the reason they take it.
• People dealing with insurance changes and comparing the shot with the newer pill.
• Researchers, app builders and sellers, who get a much cooler reception than patients.

Karma and account requirements

What it takes to get a post through in r/Semaglutide.

What you can post

What happens to a new post

Where the most recent posts ended up. Sample size: 400.

• Stayed up88%
• Removed by Reddit's filters3%
• Removed by moderators9%
• Deleted by the author1%

Reddit counts a removal by the subreddit's own AutoModerator rules as a moderator removal, so that share is not all human. Held by AutoModerator means the post is waiting in the mod queue.

What happened when we posted here

We have posted here ourselves. This is how our own posts and comments fared.

Stayed up

100%

Removed by Reddit's filters

0%

Removed by moderators

0%

Period

June 2026 to July 2026

The rules, in the mods' words

1. 1

   No compounding

   We do not allow the discussion (either explicitly or when it could be the only possible interpretation) of compounded (non-FDA-approved) semaglutide, or sources for obtaining it.

2. 2

   No selling medication

   This is not a marketplace, do not discuss selling medication (even if genuine and legally obtained).

3. 3

   No medical credentials

   Please do not claim any medical credentials, as the moderation team has no way to verify them.

4. 4

   Be nice to each other

   Make it a nice place in here! Everyone is welcome and at various stages on their weight loss and/or diabetes journey.

5. 5

   No DM's for any reason

   You may not request or provide any DM contact details. If you receive an unsolicited DM from someone in this forum, please use the "report" feature on the DM in order to report it to Reddit admins. Requesting people to DM/private message/chat you in circumvention of the rules will not be tolerated.

These are the rules as archived in January 2025. Rules change. Check the sidebar before you post.

The culture

r/Semaglutide has about 205,000 members and around 19 posts a day. The sidebar ties it to the branded semaglutide products, and the description says outright that compounded formulations are not discussed. In practice it is a patient support board: people asking whether a side effect is normal, why the scale has not moved, or what happens when insurance stops paying.

Two formats dominate. The everyday post is a short text question, around 90 words, usually with the poster's dose, timeline and weight. The top of the sub is progress photos: before and after shots with a start weight, a current weight and a few lines about how life has changed. Those pull hundreds of upvotes and a lot of congratulations. About 63% of posts are text, 28% links (mostly crossposts) and 9% images.

The live tension is the compounding ban. Plenty of members came from or are moving to cheaper routes, and posts and comments keep brushing against the rule, which is why a lot of otherwise ordinary looking posts end up removed. Side effect worries are the other constant thread: gut problems, vision, mood and hair loss all come up, and people take them seriously.

What lands

• Progress photos with honest numbers: start weight, current weight, how long it took and what else changed, like being able to kneel down or travel comfortably.
• Side effect questions asked as "how bad is yours", which let the whole room compare notes.
• First-week posts that give age, height, weight and dose and ask what to expect. They get kind, practical replies.
• Slow progress stories. A post about losing weight gradually over two years is received as warmly as a dramatic one.

What gets removed or ignored

• Anything about compounded semaglutide, including questions that only make sense if you are on it, and posts comparing online providers that sell it.
• Questions about peptide research sites, vendor purity or batch quality.
• Research surveys. A student questionnaire was removed, and members called out a poster who was mining side effect threads without saying why.
• Many ordinary looking patient posts, about stalls, dose changes or side effects, were also removed by moderators. The removed text is not visible, and the likeliest reason is a mention of where the drug came from.

The unwritten rules

• Give your numbers. Dose, weeks on it, start weight and what you are eating. Without them the replies are guesses.
• Do not name where you get your medication. Even a passing mention of a provider can sink an otherwise fine post.
• Be kind about bodies. The rules ask for it and the comments enforce it; people here are at very different stages and many have been judged before.
• Comments are short, around 23 words, and almost never carry links. A link in a reply looks like a pitch.
• If you are researching or building something, say so in the post. Members check profiles, and a hidden motive gets pointed out.

Self-promotion

There is no written self-promotion rule, but the rules ban selling medication, ban DMs for any reason, and ban talk of compounded sources, which covers most of what a brand in this space would want to post. Patient-facing tools sometimes stay up when the maker says plainly that they built it and asks for criticism. Surveys, provider comparisons and anything that reads like a referral are removed or picked apart in the comments. The safest way in is to answer questions from experience and leave products out.

How people write here

Typical post length

89 words

Typical title length

6 words

Titles phrased as a question

33%

Typical comment length

23 words

Comments that include a link

1%

The regulars

The accounts that showed up most in our sample. Worth reading before you post: they set the tone, and they are usually the first to reply.

Top keywords

The words and phrases that show up far more often here than in other communities, from recent posts in r/Semaglutide.

• semaglutide 89 posts
• weight 103 posts
• dose 85 posts
• wegovy 57 posts
• lbs 52 posts
• glp-1 36 posts
• weight loss 40 posts
• sema 26 posts
• effects 45 posts
• lost 53 posts
• ozempic 29 posts
• side effects 38 posts
• lose 41 posts
• food 43 posts
• medication 31 posts
• taking 45 posts
• side 51 posts
• appetite 24 posts
• shot 26 posts
• eating 32 posts
• injection 22 posts
• pill 16 posts
• food noise 20 posts
• doctor 26 posts
• nausea 19 posts
• doses 18 posts
• glp1 15 posts
• pounds 21 posts
• lost lbs 15 posts
• pen 15 posts
• feeling 32 posts
• eat 28 posts
• starting 38 posts
• lose weight 13 posts
• wegovy pill 10 posts
• calorie 12 posts
• rybelsus 6 posts
• dosage 15 posts
• deficit 10 posts
• taking semaglutide 6 posts

Posts that did well

• 240 lbs vs 167 lbs!!872 upvotes · 46 comments
• When you appreciate the journey more than the destination843 upvotes · 72 comments
• 8 months on Wegovy pill787 upvotes · 48 comments
• 72kg down786 upvotes · 36 comments
• One year difference. ❤️767 upvotes · 21 comments
• 4 months648 upvotes · 38 comments
• Sharing an accomplishment!557 upvotes · 33 comments
• 60 lbs down, finally happy in my own skin.517 upvotes · 12 comments

Common questions